XOLAIR is FDA-approved for use in appropriate patients with Allergic Asthma and also appropriate patients with chronic idiopathic urticaria (CIU).

XOLAIR is administered subcutaneously every 2 or 4 weeks for Allergic Asthma and every 4 weeks for CIU. 1 Because the solution is slightly viscous, the injection may take 5 to 10 seconds to administer. XOLAIR injections may be administered in your office or at an appropriate injection facility that administers XOLAIR.

What You Need to Know When Administering XOLAIR

Administer XOLAIR only in a healthcare setting by healthcare providers prepared to manage anaphylaxis that can be life-threatening. For more information on anaphylaxis, read Black Boxed Warning.

Be sure to review the full prescribing information, including Medication Guide, before administering XOLAIR to patients. Also, provide and instruct patients to read the XOLAIR Medication Guide before starting treatment and before each subsequent treatment.

XOLAIR should be shipped at a controlled ambient temperature (≤30°C [≤86°F]). Prior to reconstitution, XOLAIR should be stored under refrigerated conditions (2°C to 8°C [36°F to 46°F]). Do not use XOLAIR beyond the expiration date stamped on the carton. If the XOLAIR prescribed for a labeled indication was spoiled or unable to be administered, the Genentech Spoilage Replacement Program might be able to provide you with a new supply.*

*Subject to certain limitations and conditions. The Spoilage Replacement Program covers infused or injected Genentech products.

Supplies Needed to Administer XOLAIR

Once the correct dose has been determined and the necessary supplies have been assembled, you are ready to begin.

Preparation & Administration

Watch the video, and/or click the tabs below, to learn more about how to prepare the XOLAIR vial, reconstitute the dose, and administer the injection. 

Preparing the Vial

Reconstituting the Dose of XOLAIR

Preparing the Reconstituted Dose of XOLAIR for Subcutaneous Use

Administering the Subcutaneous Injection for XOLAIR

Spoilage Replacement Program

If the XOLAIR prescribed for a labeled indication was spoiled and unable to be administered, the product might be eligible for replacement through the Genentech Spoilage Replacement Program

Contact a Representative

Fill out a contact form to get in touch with a Genentech representative to find out more about XOLAIR.