Allergic Asthma is the most prevalent form of asthma. Approximately 60% of asthma patients have Allergic Asthma 2 and 75% of patients aged ≥12 years with moderate to severe asthma were found to have Allergic Asthma in a separate study. 3 For pediatric asthma patients, prevalence of Allergic Asthma grows to 4 out of 5. 4 For appropriate asthma patients 6 years of age and older, when you know it’s Allergic Asthma, think XOLAIR.

IgE, immunoglobulin E.


XOLAIR is for patients aged 6 years and older with moderate to severe persistent Allergic Asthma who are uncontrolled on inhaled corticosteroids (ICS). 1

Additional Information

  • XOLAIR is the only FDA-approved biologic drug specifically designed to treat Allergic Asthma
  • More than 200,000 patients 12 years of age and older have been prescribed XOLAIR since approved in 2003 (based on US data) 10

Find out more about when to consider XOLAIR for Allergic Asthma.

XOLAIR for Appropriate Allergic Asthma Patients 6 Years or Older

Who Might Be Appropriate for XOLAIR?

Patients with moderate to severe asthma 1:

  • Uncontrolled on ICS
  • With sensitivity to a perennial aeroallergen (eg, dust mites, pet dander, cockroach debris)
  • Aged ≥6 years

Patients aged 6 to <12 years 1:

  • Total IgE level of ≥30 to 1300 IU/mL
  • Body weight of 44 to 330 pounds

Patients aged ≥12 years 1:

  • Total IgE level of ≥30 to 700 IU/mL
  • Body weight of 66 to 330 pounds

To learn more about the efficacy and safety of XOLAIR for appropriate Allergic Asthma patients, view the clinical studies.

Find out more about when the National Heart, Lung, and Blood Institute (NHLBI) Guidelines recommend XOLAIR in patients 12 years and older.

XOLAIR Mechanism of Action (MOA)—Designed to Target IgE 1

XOLAIR is the only biologic specifically designed to block IgE, which limits the release of mediators in the early and late phases of the allergic inflammatory cascade 1,5-7

  • Limits mast cell degranulation 6
  • Downregulates high-affinity IgE receptors (FcεRI) 1

XOLAIR is a recombinant, DNA-derived, humanized IgG1κ monoclonal antibody. 1

XOLAIR is not indicated for other allergic conditions.

IgG1κ, immunoglobulin G1κ.

Learn more about IgE and the specific IgE tests that can be used to help confirm an Allergic Asthma diagnosis in your patients.