MECHANISM OF ACTION
MECHANISM OF ACTION
MECHANISM OF ACTION
*Based on preclinical models.
†Safety and efficacy have not been established in other allergic conditions.4
FcεRI=human IgE receptor; IgE, immunoglobulin E; IL=interleukin.
In CRSwNP, after repeated dosing of XOLAIR every 2 or 4 weeks at the recommended doses and frequency, the mean predose free IgE concentrations were reduced by:
In both CRSwNP trials, patients’ mean predose free IgE concentrations remained stable from Week 16 to Week 24 of treatment.
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Data on file. Genentech USA, Inc. South San Francisco, CA.
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